ACETOACETATE REDUCES GROWTH AND ATP CONCENTRATION IN CANCER CELL LINES WHICH OVER-EXPRESS UNCOUPLING PROTEIN 2

Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2

Abstract Background Recent evidence suggests that several human cancers are capable of uncoupling of mitochondrial ATP generation in the presence of intact tricarboxylic acid (TCA) enzymes.The goal of the current study was to test the hypothesis that ketone bodies can inhibit cell growth in aggressive cancers and that expression of uncoupling prote

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Probabilistic Path Planning for UAVs in Forest Fire Monitoring: Enhancing Patrol Efficiency through Risk Assessment

Forest fire is a significant global natural disaster, and unmanned aerial vehicles (UAVs) have gained attention in wildfire prevention for their efficient and flexible monitoring capabilities.Proper UAV patrol path planning can enhance fire-monitoring accuracy and response speed.This paper proposes a probabilistic path planning (PPP) module that pl

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Lead exposure from soil in Peruvian mining towns: a national assessment supported by two contrasting examples

OBJECTIVE: To estimate the population of Peru living in the vicinity of active or former mining operations that could be Supplemental Feeding exposed to lead from contaminated soil.METHODS: Geographic coordinates were compiled for 113 active mines, 138 ore processing plants and 3 smelters, as well as 7743 former mining sites.The population living w

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